Etiology of diabetes mellitus

May 05, 2018 13:00 | Symptoms And Treatment
Acute childhood infections, of course, contribute to the onset of diabetes in children. According to MM Bubnova and Martynova, such infections include epidemic parotitis, chicken pox, measles;here you can include influenza and angina. The significance of infections as a factor in the onset of diabetes mellitus is indicated by MG Daihez, D. D. Sokolov, E. L. Belikhova.

All this makes it possible to recommend a urine test for sugar in children one month after transferring them to one or another infection.

Mental and physical trauma .Many authors attribute a certain role in the development of diabetes mellitus to mental and physical trauma, and some even link it directly to a recent trauma.

However, numerous data on the course of diabetes mellitus in adults do not allow to join unquestionably to this point of view. Apparently, the mental and physical trauma only contributes to the early detection of the latent diabetes mellitus, i.e., the inferiority of the insular apparatus is manifested in the period of increased demands to it, especially with repeated injuries or stressful reactions.

We observed the development of diabetes in a girl 6 years shortly after a physical trauma: 2 weeks after a severe blow to her stomach, she felt thirsty, the girl began to lose weight, and the study found 5% sugar in the urine, which required the introduction of insulin.

At the boy of 9 years the diabetes mellitis, according to mother, has been revealed after strong fright - on the child the dog which has broken from a chain has rushed. After 8 days he developed a strong thirst, he began to noticeably lose weight, and sugar was found in the urine in an amount of 6%.

Generally, hyperglycemia and glycosuria after a mental and physical trauma are common, but they usually disappear soon and diabetes does not develop.

Excessive nutrition, undoubtedly, badly affects the condition of the insular apparatus. Samples with a sugar load in people who have been overweight for many years, as a rule, are more often the nature of the samples with the secretive diabetes mellitus.

SG Genes, NS Weller believe that diabetes is more common in people who eat mainly fats: it's not carbohydrates, but fats with excessive administration contribute to the depletion of beta cells. This is confirmed by statistical observations and experimental studies.

But still the excessive use of sweets by children can not but lead to an increase in the function of the insular apparatus. According to MM Bubnova and Martynova, out of 140 children with diabetes mellitus, 10% had a history of excessive consumption of sweets for a long time.

With excessive nutrition for increased secretion of insulin, the weight of the food taken is also important.

The role of age is .Most authors who studied the features of diabetes in children, indicates that the incidence of diabetes mellitus at 6-8 and 11-13 years increases more significantly than in other childhood periods.

The higher incidence is precisely in these years due to the fact that the insular apparatus during the most intensive growth is subject to great demands. Diabetes mellitus can develop at any age. It describes the cases of the disease of one-year-old children and even in the first weeks of life.

Currently, it is estimated that of all cases of diabetes, about 5% falls on the age of up to 10 years.

The role of heredity: Steinberg and Jackson believe that diabetes can also be a hereditary disease, as often the parents of children with diabetes have insulin deficiency.

According to VM Kogan-Yasny, diabetes mellitus develops as a hereditary disease in 10-47% of such patients.

Numerous clinical observations show that diabetes is often noted among members of the same family, but different authors give different data about this. So, D.D. Sokolov, hereditary factor was detected in 7% of patients with diabetes mellitus, Grot - in 53.2%, Hestom - in 30%, Eisel - in 62%, A.Bialik - in 13.3% of patients.

Apparently, the difference in indicators depends on the method of assessing hereditary factors: when examining the state of the insular apparatus of parents of sick children, its violations are detected much more often than when studying only anamnesis.

In recent years, very interesting experimental data have been obtained in this field. Thus, with alloxan damage to the insular apparatus of rabbits, there was a marked weakening in the offspring, which is growing in subsequent generations, and a progressive decrease in the number of beta cells;Diabetes mellitus developed even without the use of alloxan.

The issue under consideration, unfortunately, has not yet been properly studied, but the data already available should be taken into account in the implementation of preventive measures - primarily in the nutrition of the child.
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