Cytomegalovirus hepatitis in newborns
Diagnosis of isolated( jaundiced) cytomegalovirus hepatitis in the absence of damage to other systems is very difficult. In favor of this peculiar etiology may be a combination, albeit impermanent, of externally isolated hepatitis with chorioretinitis. Nonspecific inflammatory reactions( IgC and IgM, sediment assays) that are often positive very early are important.
Evidence of cytomegalovirus infection is currently more convincing, since the available serological methods, following the example of rubella, allow for undeniable diagnosis. These include the technique of indirect agglutination and titration of specific antibodies in various immunoglobulins.
The need for a culture of cytomegaloviruses from blood, urine, cerebrospinal fluid or saliva in any child suspected of cytomegalovirus hepatitis is currently less significant than before. This study can be repeated, since the child continues to isolate the virus within a few weeks after the onset of clinical manifestations of the disease. The definition of cells with inclusions in the urine sediment is almost not carried out at present.
Histological examination of the liver with septicemic or isolated forms of cytomegalovirus hepatitis reveals a pronounced inflammatory response and sometimes cytomegalic inclusions in the parenchyma or biliary tubules.
Women's magazine www. BlackPantera.en: Alajill Odyevr